Marianne Koritzinsky, PhD
Princess Margaret Cancer Centre
University Health Network
Assistant Professor and Director of Research
Department of Radiation Oncology and Institute of Medical Science
University of Toronto
Dr. Koritzinsky is a recipient of the ESTRO-Juliana Denekamp research award, the Terry Fox Research Institute New Investigator award, and the Radiation Research Society Michael Fry award.
Tumor hypoxia confers poor patient prognosis due to resistance to radiation and chemotherapy, and stimulation of a more aggressive phenotype. The aim of Dr. Koritzinsky’s research program is to increase our understanding of molecular and cellular responses to hypoxia, with the ultimate goal of targeting these responses to improve cancer treatment efficacy, mitigate cancer aggressiveness and improve patient outcomes. Research is focused on determining how cancer cells adapt metabolism and secretion capacity in hypoxia, and therapeutic strategies to reprogram tumor metabolism. Dr. Koritzinsky is also actively engaged in education, and she is Director of “Clinical and Experimental Radiobiology” and co-Director of “Strategic Training in Transdisciplinary Radiation Science” (STARS21), two pan-Canadian educational programs.